| 名稱 | BCR-ABL1 Q252H/BaF3 |
| 型號(hào) | CBP73289 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | BCR-ABL1 [Q252H]/BaF3,母細(xì)胞：BaF3，凍存條件：90% FBS+10% DMSO； |
產(chǎn)品搜索
相關(guān)文章
- NK2R細(xì)胞篩選模型
- 是激活還是沉默？基因表達(dá)的新路徑
- 喝熱茶或使食管癌風(fēng)險(xiǎn)增加5倍
- 聚焦靶點(diǎn)BRAF——BRAF相關(guān)突變細(xì)胞強(qiáng)勢(shì)登場(chǎng)
- 中國(guó)細(xì)胞資源庫(kù)，南京科佰生物
- 一個(gè)蛋白竟可同時(shí)影響乳腺癌和淋巴癌的形成與擴(kuò)散
- PIM-1激酶抑制劑細(xì)胞篩選模型
- atcc細(xì)胞的細(xì)胞核分離原理說(shuō)明
- 你學(xué)會(huì)細(xì)胞傳代的操作步驟了嗎？
- OX40&PD-1/L1雙免疫檢查點(diǎn)細(xì)胞篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73289BCR-ABL1 Q252H/BaF3
- 詳細(xì)內(nèi)容
| CBP73289 | |
| I. Introduction | |
Cell Line Name： | BCR-ABL1 [Q252H]/BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
ABL1, ABL proto-oncogene 1, non-receptor tyrosine kinase, plays a role in regulation of cell growth through ERK5, Rac/JNK, and Stat1/3 pathways (PMID: 10373409). Fusion proteins of BCR-ABL1 resulting in constitutive kinase activity have been reported in various cancers (PMID: 18851712, PMID: 30125955) and a number of Abl1 mutations in the context of BCR-ABL1 have been demonstrated to confer drug resistance (PMID: 24456693). | |
| III. Representative Data | |
1.WB of BCR-ABL1 [Q252H]/BaF3
| |
2. Sanger of BCR-ABL1 [Q252H]/BaF3
Figure 2. BCR-ABL1 [Q252H]/BaF3 Fusion
Figure 3. BCR-ABL1 [Q252H]/BaF3 Q252H | |
3. Anti-proliferation assay | |
Figure 4. CTG Proliferation Assay of BaF3 BCR-ABL1 Q252H Cells (C1). | |
會(huì)員_a.png)