| 名稱 | Her2 A775_G776insYVMA/BaF3 | 
| 型號 | CBP73184 | 
| 報(bào)價(jià) | ![]()  | 
								
| 特點(diǎn) | Her2 A775_G776insYVMA/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO | 
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					產(chǎn)品展示  / PRODUCTS
					
						藥靶細(xì)胞株 > kinase激酶細(xì)胞株  >  CBP73184Her2 A775_G776insYVMA/BaF3
            
              
					
				
				
						- 詳細(xì)內(nèi)容
 
| CBP73184 | |
| I. Introduction | |
Cell Line Name:  | Her2 A775_G776insYVMA/BaF3  | 
Host Cell:  | Ba/F3  | 
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | 
Application:  | Anti-proliferation assay and PD assay  | 
Freeze Medium:  | 90% FBS+10% DMSO  | 
Complete Culture Medium:  | RPMI-1640+10%FBS  | 
Mycoplasma Status:  | Negative  | 
| II.Background | |
ERBB2 (HER2) A775_G776insYVMA results in the insertion of four amino acids in the protein kinase domain of the Erbb2 (Her2) protein between amino acids 775 and 776 (UniProt.org). A775_G776insYVMA results in the same amino acid change as M774_A775insAYVM, which leads to constitutive phosphorylation of Erbb2 (Her2) and is transforming in cell culture (PMID: 17311002, PMID: 29967253).  | |
| III. Representative Data | |
1. WB of Her2 A775_G776insYVMA/BaF3 
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2. Anti-proliferation assay  | |
 Figure 2. Anti-proliferation assay of two reference compounds on the Her2 A775_G776insYVMA/BaF3 Stable Cell Line  | |






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