名稱 | CCR5/CHO |
型號(hào) | CBP71352 |
報(bào)價(jià) | ![]() |
特點(diǎn) | CCR5/CHO 凍存條件:90% FBS+10% DMSO |
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藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71352CCR5/CHO

- 詳細(xì)內(nèi)容
CBP71352 | |
I. Background | |
C-C chemokine receptor type 5 (CCR5) is a G protein-coupled receptor and a co-receptor for the entry of human immunodeficiency virus-1 (HIV-1) into cells. CCR5 chemokine receptor is involved in leucocytes chemotaxis to sites of inflammation and plays an important role in the macrophages, T cells, and monocytes recruitment. The chemokine ligands that bind to CCR5 are regulated on activation, normal T Cell expressed and secreted (RANTES) and macrophage inflammatory protein 1 alpha (MIP1α). GenScript’s human CCR5-expressing stable subline is guaranteed to function properly in the calcium flux assay. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5ug/ml puromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for CCR5 receptor |
Transducer: | N/A |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
![]() | |
Figure 2. CCL 4 effect on CCR5/CHO-K1 clone 4. |