| 名稱 | AI-Edigene® KRAS p.Q61H Reference Standard Pl |
| 型號 | CBP10430 |
| 報價 |  |
| 特點 | AI-Edigene® KRAS p.Q61H Reference Standard Plus |
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Email： zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10430AI-Edigene® KRAS p.Q61H Reference Standard Pl
- 詳細內(nèi)容
CBP10430 | |
| Format | Genomic DNA |
| Description | KRAS Q61H is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). Q61H results in decreased GTPase activity in the Kras protein, increased downstream signaling, and transformation of cultured cells (PMID: 20147967). |
| Technical Data | |
| DNA Change | c.183A>C |
| AA Change | p.Q61H |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000311936 |
| Cosmic ID | COSM554 |
| Chr position(GRCh37) | chr12:25380275 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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